Extracranial growth of glioblastoma multiforme.

CASE REPORT Multiple extracranial metastases from secondary glioblastoma multiforme: a case report and review of the literature

Extracranial metastasis of glioblastoma multiforme (GBM) is very rare, in spite of very aggressive tumor behavior and being documented in only a few patients. In this article we present a 25-year-old man with secondary glioblastoma associated with extracranial progression and distant metastasis. He was diagnosed by magnetic resononce (MR) with an intracranial lesion in the right parietofrontal ...

Fine needle aspiration diagnosis of extracranial glioblastoma multiforme: Case report and review of the literature

BACKGROUND Hitherto uncommon, the incidence of extracranial metastases of primary brain malignancies may increase, with improved treatment methods and longer patient survival. Fine needle aspiration biopsy is a simple, safe and reliable method to diagnose metastatic malignancy. It has definite advantages over tissue biopsy, which is more invasive and is of higher risk to the patient. Ours is a ...

Extracranial metastasis of multiforme glioblastoma detected by 11C-methionine brain PET/CT.

Meningeal seeding from glioblastoma multiforme treated with radiotherapy and temozolomide.

Extracranial and meningeal seeding of glioblastoma multiforme is rare. We report herein a case of glioblastoma in a 41-year-old man who underwent surgical resection, concomitant chemoradiotherapy (CCRT) and seven courses of adjuvant chemotherapy with temozolomide. The patient then complained of intermittent severe lower back pain and gait disturbance. Imaging studies demonstrated that although ...

Glioblastoma Multiforme in Children, A Case-Report

ABSTRACT: Glioblastoma multiforme is the most malignant primary brain tumor .It usually occurs in the 5th and 6th decades of life and is rare in childern. In this paper a case of glioblastoma multiforme is reported in a ten year - old child who presented with two week's history of headache with no neurological defect.C.T scan revealed å right frontal mass with massive surrounding oedema. He w...

Antiglioma immunological memory in response to conditional cytotoxic/immune-stimulatory gene therapy: humoral and cellular immunity lead to tumor regression.

PURPOSE Glioblastoma multiforme is a deadly primary brain cancer. Because the tumor kills due to recurrences, we tested the hypothesis that a new treatment would lead to immunological memory in a rat model of recurrent glioblastoma multiforme. EXPERIMENTAL DESIGN We developed a combined treatment using an adenovirus (Ad) expressing fms-like tyrosine kinase-3 ligand (Flt3L), which induces the ...